New Preprint - Identification of chemical features that influence mycomembrane permeation and antitubercular activity

https://www.biorxiv.org/content/10.1101/2025.02.27.640664v1

In collaboration with microbiology and chemistry colleagues, we built a model to predict the permeability of any chemical compound through the outer membrane of Mycobacterium tuberculosis. Permeability is an important prerequisite for a compound to be an effective antibiotic.