SAGE Lab

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The Sequence Analysis and Genomics lab at UMass Amherst aims to build and apply computational methods to understand genetic variation. We have a particular emphasis on antibiotic resistant bacteria, which pose a major and evolving public health threat.

Using machine learning combined with a deep understanding of molecular biology and bacterial genomics, we build models that predict antibiotic resistance from genome sequences, and provide interpretable outputs about the genetic basis of resistance.